发明名称 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
摘要 Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, A, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
申请公布号 US2013336920(A1) 申请公布日期 2013.12.19
申请号 US201313734547 申请日期 2013.01.04
申请人 ARDELYX, INC.;ARDELYX, INC. 发明人 LEWIS JASON G.;JACOBS JEFFREY W.;REICH NICHOLAS;LEADBETTER MICHAEL R.;BELL NOAH;CHANG HAN-TING;CHEN TAO;NAVRE MARC;CHARMOT DOMINIQUE;CARRERAS CHRISTOPHER;LABONTE ERIC
分类号 C07D213/81;A61K31/44;A61K31/4545;A61K31/506;A61K31/5377;A61K31/541;A61K31/551;A61K31/59;A61K31/785;A61K45/06;C07D401/10;C07D401/14;C07D405/14;C07D417/14 主分类号 C07D213/81
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