发明名称 Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom
摘要 1H-Imidazo[4,5-c]quinolin-4-amines substituted at the 1-position with a substituent bearing a hydrazinobenzamide or hydrazinonicotinamide, a salt thereof, or a protected hydrazinobenzamide or hydrazinonicotinamide and conjugates made from such compounds are disclosed. Pharmaceutical compositions containing the compound or the conjugate, methods of making a conjugate, and methods of use of the compounds or conjugates as immunomodulators for inducing cytokine biosynthesis in an animal and for vaccinating an animal are also disclosed.
申请公布号 AU2012261959(A1) 申请公布日期 2013.12.19
申请号 AU20120261959 申请日期 2012.06.01
申请人 3M INNOVATIVE PROPERTIES COMPANY 发明人 WIGHTMAN, PAUL D.
分类号 C07D471/04;A61K31/437;A61P31/12;A61P35/00 主分类号 C07D471/04
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