发明名称 |
CHEMILUMINESCENCE-BASED HAEMOSTASIS ASSAY |
摘要 |
The present invention relates to a method for in vitro determining generation of a haemostatis factor such as thrombin and/or plasmin in a test sample using a chemiluminescent substrate specific for said blood clotting factor. Upon cleavage of the substrate, a luminescent signal is generated via aminoluceferin with the aid of a luciferase. The invention also relates to a kit for in vitro determining generation of a haemostasis factor in a test sample, and to novel chemiluminescent substrates for the determination of thrombin and plasmin. |
申请公布号 |
US2013337480(A1) |
申请公布日期 |
2013.12.19 |
申请号 |
US201113993992 |
申请日期 |
2011.12.14 |
申请人 |
VAN HEERDE WAANDER LAURENS;BLAAUW RICHARD HENDRIK;CHIRALIX B.V.;STICHTING KATHOLIEKE UNIVERSITEIT |
发明人 |
VAN HEERDE WAANDER LAURENS;BLAAUW RICHARD HENDRIK |
分类号 |
C12Q1/66;C12Q1/37;C12Q1/56 |
主分类号 |
C12Q1/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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