| 摘要 |
The method for the production of a layered-wound pad with a biocompatible material and polysaccharides, comprises providing a dispersion of polysaccharides in a fluid dispersion agent, hardening the dispersion under layered formation of polysaccharides through the reception of water from fluid dispersion agent and/or the reception of the dispersion agent in the polysaccharides and/or through evaporation of the dispersion agent, swelling the hardened polysaccharides through the supply of water under formation of gel. The method for the production of a layered-wound pad with a biocompatible material and polysaccharides, comprises providing a dispersion of polysaccharides in a fluid dispersion agent, hardening the dispersion under layered formation of polysaccharides through the reception of water from fluid dispersion agent and/or the reception of the dispersion agent in the polysaccharides and/or through evaporation of the dispersion agent, swelling the hardened polysaccharides through the supply of water under formation of gel and/or adjusting its thickness and pore structure, applying a suspension or solution of biocompatible material on the swollen gel or the layered, hardened polysaccharides, and simultaneously cooling off and freeze-drying of gel with the suspension or solution of biocompatible materials or the hardened polysaccharides with the suspension or solution of the biocompatible material under formation of solid compound between the layers. The fluid dispersion agent consists of organic water-containing fluid and/or fluids such as ethanol, isopropanol or glycerin, and/or the organic fluid consists of 15 wt.% of water. The polysaccharide dispersion consists of 20 wt.% of polysaccharide and/or 1.0 wt.% of collagen related to the total weight of the suspension. The wound-pad is produced with a thickness of 2-4 mm. The polysaccharides and/or the biocompatible materials are dyed by riboflavin for the identification of the wound pad. The wound pad consists of antimicrobial and/or anti-inflammatory material and/or the surface of the wound pad is modified or structured in wave-like manner. The wound pad is produced under use of a cross-linker such as aldehyde and/or plasticizer such as 1,2-propanediol. A new layer is applied on the frozen wound pad having a layered biocompatible material and polysaccarides and is formed under freeze-drying to a three-layered wound pad. Porcine is used as collagen. An independent claim is included for a layered-wound pad. |
