发明名称 |
1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40 |
摘要 |
<p>The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to Formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.</p> |
申请公布号 |
AU2009221087(B2) |
申请公布日期 |
2013.12.05 |
申请号 |
AU20090221087 |
申请日期 |
2009.03.05 |
申请人 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. |
发明人 |
GUGLIELMOTTI, ANGELO;MANGANO, GIORGINA;FURLOTTI, GUIDO;CAZZOLLA, NICOLA |
分类号 |
C07D231/54;A61K31/416;A61K31/435;A61P3/10;A61P9/00;A61P13/00;C07D401/12 |
主分类号 |
C07D231/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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