发明名称 |
RISPERIDONE OR PALIPERIDONE IMPLANT FORMULATION |
摘要 |
<p>The present invention is directed to an injectable intramuscular depot composition suitable for forming an in situ solid implant in a body, comprising a drug which is risperidone and/or paliperidone or any pharmaceutically acceptable salt thereof in any combination, a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid of about 50:50 and a DMSO solvent, wherein the composition releases the drug with an immediate onset of action and continuously for at least 4 weeks and wherein the composition has a pharmacokinetic profile in vivo that makes it suitable to be administered each 4 weeks or even longer periods.</p> |
申请公布号 |
WO2013178812(A1) |
申请公布日期 |
2013.12.05 |
申请号 |
WO2013EP61320 |
申请日期 |
2013.05.31 |
申请人 |
LABORATORIOS FARMACEUTICOS ROVI, S.A. |
发明人 |
GUTIERRO ADURIZ, IBON;FRANCO RODRIGUEZ, GUILLERMO |
分类号 |
A61K47/34 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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