发明名称 STABILIZED FORMULATIONS CONTAINING ANTI-DLL4 ANTIBODIES
摘要 The present invention provides pharmaceutical formulations comprising an antibody that specifically binds to human delta-like ligand 4 (Dll4). The formulations may contain, in addition to an anti-Dll4 antibody, a phosphate buffer, an organic cosolvent, a disaccharide, and a salt. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months and after being subjected to thermal and other physical stress
申请公布号 US2013323260(A1) 申请公布日期 2013.12.05
申请号 US201313906479 申请日期 2013.05.31
申请人 REGENERON PHARMACEUTICALS, INC. 发明人 WALSH SCOTT;DIX DANIEL
分类号 A61K39/395 主分类号 A61K39/395
代理机构 代理人
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