发明名称 |
MODULATING RESPONSIVENESS TO STEROIDS |
摘要 |
The present invention makes it possible to enhance steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an effective to said patient amount of an oligonucleotide comprising the sequence TTCGT and having a total length of up to 100 nucleotides. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals. |
申请公布号 |
PT2179737(E) |
申请公布日期 |
2013.12.05 |
申请号 |
PT20090167538T |
申请日期 |
2006.06.30 |
申请人 |
INDEX PHARMACEUTICALS AB |
发明人 |
ANN-KRISTIN SPIIK;ROBERT LOEFBERG;OLIVER VON STEIN;AREZOU ZARGARI |
分类号 |
A61K31/7088;A61K31/712;A61K31/7125;A61K45/06;A61P29/00;C12N15/117 |
主分类号 |
A61K31/7088 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|