发明名称 Reversible fluorescence photoswitch based on dye-crosslinked dendritic nanoclusters for high-contrast imaging of living biological systems
摘要 PURPOSE: A reversible fluorescence photoswitch for high-contrast imaging based on a dendrimer nanocluster structure crosslinked by photochromic compounds is provided to improve detection sensitivity and to ensure high safety. CONSTITUTION: A reversible fluorescence photoswitch for high-contrast imaging based on dendrimer nanocluster structure crosslinked by photochromic compounds has a plurality dendrimers surrounding a dendrimer at the center. Each dendrimer is connected to the end of adjacent drimers by one or more crosslinking agent. The photochromic material is an azobenzene derivative, spiropyran derivative, diarylethene derivative, or fulgide derivative. The dendrimer is polyamidoamine(PAMAM) dendrimer, polylysine dendrimer, polypropylene imine(PPI) dendrimer, polyester dendrimer, polyglutamic acid dendrimer, polyaspartic acid dendrimer, or polymelamin dendrimer.
申请公布号 KR101334696(B1) 申请公布日期 2013.12.02
申请号 KR20110084771 申请日期 2011.08.24
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分类号 A61K31/38;A61K47/48;A61K49/12;A61K49/14 主分类号 A61K31/38
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