摘要 |
<p>Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.</p> |
申请人 |
SIGNAL PHARMACEUTICALS, LLC |
发明人 |
BENNETT, BRYDON, L.;ELSNER, JAN;ERDMAN, PAUL;HILGRAF, ROBERT;LEBRUN, LAURIE, ANN;MCCARRICK, MEG;MOGHADDAM, MEHRAN, F.;NAGY, MARK, A.;NORRIS, STEPHEN;PAISNER, DAVID, A.;SLOSS, MARIANNE;ROMANOW, WILLIAM, J.;SATOH, YOSHITAKA;TIKHE, JAYASHREE;YOON, WON, HYUNG;DELGADO, MERCEDES |