发明名称 1,3-dihydroimidazol-2-thione derivatives as inhibitors of dopamine-beta-hydroxylase
摘要 <p>Compounds of formula I and a method for their preparation are described: where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; R4 signifies -alkyl-aryl or -alkyl-heteroaryl; X signifies CH2, oxygen atom or sulphur atom; n is 2 or 3; including the individual (R)- and (S)-enantiomers or mixtures of enantiomers thereof; and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.</p>
申请公布号 IL201921(A) 申请公布日期 2013.11.28
申请号 IL20090201921 申请日期 2009.11.04
申请人 BIAL-PORTELA & C.A. S.A 发明人
分类号 A61K;A61P;C07D 主分类号 A61K
代理机构 代理人
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