| 摘要 |
PURPOSE: A method for making a wormwood fermentation and a patch device using the wormwood fermentation are provided to penetrate active ingredients of the fermentation onto epidermis and to ensure anti-inflammatory, antibacterial, and antifungal functions. CONSTITUTION: A method for making a wormwood fermentation comprises: a step of drying wormwood under the shade at room temperature; a step of adding 2L of ethanol to 1.0 kg of the wormwood and shaking for 8 hours; a step of filtering the ethanol extract using a filter paper by reduced pressure; a step of concentrating the filtered liquid at 45-55 Deg. C. by compression to prepare soft extract; a step of mixing 200g of the soft extract and 200 ml of enzyme solution containing beta-glucosidase in a fermentation tank; and a step of fermenting and maturing the mixture at 45-55 Deg. C. for 48 hours. The method further comprises: a step of adding 12g of carbomer 940 to 500 ml of purified water and mixing with the fermentation; a step of adding 50g of labrasol, 100g of propylene glycol, and 30g of ethanol and shaking; and a step of adding triethanol amine and incubating the final mixture at 4 Deg. C. for 24 hours. [Reference numerals] (AA) Adhesive patch; (BB) Wormwood-fermented gel; (CC) Epidermis; (DD) Drug; (EE) Dermis; (FF) Blood vessel; (GG) Subcutaneous tissue/fascia; (HH) Deep fascia; (II) Muscle; (JJ) Vein; (KK) Artery |
