发明名称 |
CCR6 As A Biomarker of Alzheimer's Disease |
摘要 |
Disclosed are methods used to diagnose Alzheimer's disease (AD) in a subject. The methods involve determining the amount of chemokine receptor 6 (CCR6) expressed in a biological sample. Expression of CCR6 in the sample that exceeds a threshold level of expression signifies that the subject has AD, even if the subject has not yet developed symptoms of AD. The methods may also be used to monitor the effectiveness of an AD treatment. Kits that facilitate the use of the methods are also disclosed.
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申请公布号 |
US2013316338(A1) |
申请公布日期 |
2013.11.28 |
申请号 |
US201113806394 |
申请日期 |
2011.06.28 |
申请人 |
OFFNER-VANDENBARK HALINA;QUINN JOSEPH F.;SUBRAMANIAN SANDHYA;THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS;OREGON HEALTH & SCIENCE UNIVERSITY |
发明人 |
OFFNER-VANDENBARK HALINA;QUINN JOSEPH F.;SUBRAMANIAN SANDHYA |
分类号 |
C12Q1/68;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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