发明名称 |
USE OF BETA-ADRENERGIC INVERSE AGONISTS FOR SMOKING CESSATION |
摘要 |
<p>The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a p-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. The invention further encompasses pharmaceutical compositions comprising the p-adrenergic inverse agonist and the additional compound.</p> |
申请公布号 |
EP2665741(A2) |
申请公布日期 |
2013.11.27 |
申请号 |
EP20120734378 |
申请日期 |
2012.01.09 |
申请人 |
INVION, INC |
发明人 |
BOND, RICHARD, A.;GLASS, MITCHELL |
分类号 |
A61K31/138;A61K9/68;A61K9/70;A61K31/403;A61K31/5377;A61K45/06;A61P25/34 |
主分类号 |
A61K31/138 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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