| 发明名称 |
Imidazo[1,2-a]pyridines and imidazo[1,2-b]pyridazines as mark inhibitors |
| 摘要 |
The invention encompasses imidazo[1,2-a]pyridine and imidazo[1,2-b]pyridazine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. Pharmaceutical compositions and methods of use are also included.
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| 申请公布号 |
US8592425(B2) |
申请公布日期 |
2013.11.26 |
| 申请号 |
US201013144123 |
申请日期 |
2010.01.12 |
| 申请人 |
ALTMAN MICHAEL D.;BILODEAU MARK T.;LIM JONGWON;NORTHRUP ALAN;STANTON MATTHEW G.;TAOKA BRANDON M.;MERCK SHARP & DOHME CORP. |
发明人 |
ALTMAN MICHAEL D.;BILODEAU MARK T.;LIM JONGWON;NORTHRUP ALAN;STANTON MATTHEW G.;TAOKA BRANDON M. |
| 分类号 |
A01N43/58;A61K31/50;C07D487/00 |
主分类号 |
A01N43/58 |
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