发明名称 |
PHARMACEUTICAL COMPOSITIONS FOR THE DELIVERY OF SUBSTANTIALLY WATER-INSOLUBLE DRUGS |
摘要 |
<p>The subject invention relates to compositions and methods useful for the in vivo delivery of substantially water-insoluble drugs, like taxol. The use of specific composition and preparation conditions enables the reproducible production of unusually water -soluble formulation, which can be sterile-filtered. The particulate system produced according to the invention can be converted into a re-dispersible dry powder comprising nanoparticles of drug. The innovation is also based on the fact that complementary partner is also an active drug but may have a different mode action with respect to primary molecule of the hybrid drug. The complementary molecule has multiple properties like antioxidant, antimicrobial, anti-inflammatory, anti-allergic, cox-2 inhibitors, etc. This results in a unique delivery system, in which part of the pharmacologically active agent is readily bioavailable.</p> |
申请公布号 |
CA2873572(A1) |
申请公布日期 |
2013.11.21 |
申请号 |
CA20132873572 |
申请日期 |
2013.04.09 |
申请人 |
SINGH, MEWA;SANDHU, MANINDER |
发明人 |
SINGH, MEWA;SANDHU, MANINDER |
分类号 |
A61K36/9066;A61K31/337;A61P9/00;A61P25/28;A61P29/00;A61P35/00 |
主分类号 |
A61K36/9066 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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