发明名称 |
SYSTEM AND METHOD FOR GENERATION AND USE OF OPTIMAL NUCLEOTIDE FLOW ORDERS |
摘要 |
An embodiment of a method for generating a flow order that minimizes the accumulation of phasic synchrony error in sequence data is described that comprises the steps of: (a) generating a plurality of sequential orderings of nucleotides species comprising a k-base length, wherein the sequential orderings define a sequence of introduction of nucleotide species into a sequencing by synthesis reaction environment; (b) simulating acquisition of sequence data from one or more reference genomes using the sequential orderings, wherein the sequence data comprises an accumulation of phasic synchrony error; and (c) selecting one or more of the sequential orderings using a read length parameter and an extension rate parameter. |
申请公布号 |
CA2873146(A1) |
申请公布日期 |
2013.11.21 |
申请号 |
CA20132873146 |
申请日期 |
2013.05.16 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
CHEN, YI-JU;WONG, CHIU TAI A. |
分类号 |
G06F19/22 |
主分类号 |
G06F19/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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