PRIMER COMPOSITION FOR AMPLIFYING A GENE REGION HAVING VARIOUS VARIATIONS IN A TARGET GENE
摘要
The present invention provides a primer composition for amplifying a gene region having various variations in a target gene comprising: a first primer group comprising at least one primer specific to at least one template including a genotype-analyzable sequence of a genetically variant base sequence subjected to be analyzed in the target gene; and a second primer group comprising at least one primer designed by selecting one primer having the greatest number of shared bases from the primers of the first primer group and by using the selected primer as a reference, the primer of the second primer group binding specifically to the template or binding complementarily to the template with allowing mismatch of up to three successive bases or 1 to 2 bases in the vicinity of the 3' end of the template.
申请公布号
EP2568052(A4)
申请公布日期
2013.11.20
申请号
EP20110777513
申请日期
2011.04.20
申请人
GENEMATRIX INC.
发明人
YOO, WANGDON;HWANG, SUN YOUNG;SHIN, SOO-KYUNG;SHIN, JI YOUNG;LEE, JOO HYOUNG;PARK, SUN MIN;HONG, SUN PYO;KIM, SUKJOON;KIM, SOO-OK