发明名称 Aminopyrazine derivative and medicine
摘要 The present invention relates to a compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutically acceptable salt of the compound. (I) is CH or N; R1 is a halogen atom; and R2 is H, a halogen atom, CN, [2], [3], [8], [9], an -O-alkyl, an -O- (saturated ring), etc. [2]: -C(RC)(RD)(RE) (RC to RE each are H, an alkyl, etc.) [3]: -N(RF)(RG) (RF and RG each are H, OH, amino, a (hetero)aryl, etc.) [8]: -C(=O)RL (RL is an alkyl, OH, an alkoxy, amino, etc.) [9]: a (substituted)phenyl; (II) X is >C-C(=O)RB (RB is a (substituted)amino, an alkoxy, OH, etc.); R1 is a halogen atom; and R2 is H; and R3 is H or OH; and R4 and R5 each are H or an alkyl.
申请公布号 US8586591(B2) 申请公布日期 2013.11.19
申请号 US201313743550 申请日期 2013.01.17
申请人 FUJIHARA HIDETAKA;ASAKI TETSUO;HORI KATSUTOSHI;NAITO HARUNA;NIPPON SHINYAKU CO., LTD. 发明人 FUJIHARA HIDETAKA;ASAKI TETSUO;HORI KATSUTOSHI;NAITO HARUNA
分类号 A61K31/497;C07D401/14 主分类号 A61K31/497
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