发明名称 PROCEDE POUR DETERMINER LA SUSCEPTIBILITE A CONTRACTER UNE INFECTION NOSOCOMIALE CHEZ UN PATIENT PRESENTANT UNE REPONSE SYSTEMIQUE INFLAMMATOIRE ASSOCIEE OU NON A UNE INFECTION.
摘要 <p>Determining susceptibility for contracting nosocomial infection in a patient having a systemic inflammatory response (non)associated with an infection, comprises collecting a biological sample from the patient and extracting biological material from biological sample; taking at least one specific reagent from an expression product of the target gene S100A9; and determining the expression of the target gene S100A9. Independent claims are included for: (1) establishing an early prognosis of survival in a patient having a systemic inflammatory response (non)associated with infection, or for determining the etiology of a systemic inflammatory response (non)associated with infection in patient, comprising (a) collecting biological sample from the patient and extracting from biological material from the biological sample, (b) collecting at least one reagent specific for an expression product of the target gene S100A9 and (c) determining the expression of the S100A9 target gene; (2) a first kit for determining susceptibility in contracting nosocomial infection in a patient having a systemic inflammatory response (non)associated with an infection comprising one reagent specific for S100A9 gene expression product; (3) use of at least one reagent for determining, in vitro, the susceptibility for contracting a nosocomial infection in a patient having systemic inflammatory response (non)associated with an infection; (4) a second kit for establishing an early prognosis for survival in a patient having a systemic inflammatory response (non)associated with an infection comprising at least one reagent specific for an expression product of S100A9 gene; and (5) use of at least one reagent for establishing, in vitro, a prognosis for survival in a patient having a systemic inflammatory response (non)associated with an infection.</p>
申请公布号 FR2941239(B1) 申请公布日期 2013.11.15
申请号 FR20090050305 申请日期 2009.01.19
申请人 BIOMERIEUX;HOSPICES CIVILS DE LYON 发明人 CAZALIS MARIE ANGELIQUE;LEPAPE ALAIN;MONNERET GUILLAUME;MOUGIN BRUNO;PACHOT ALEXANDRE
分类号 C12Q1/68;G01N33/68 主分类号 C12Q1/68
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