| 发明名称 |
IL4/IL13 binding repeat proteins and uses |
| 摘要 |
<p>IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1 ) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.</p> |
| 申请公布号 |
AU2012249359(A1) |
申请公布日期 |
2013.11.14 |
| 申请号 |
AU20120249359 |
申请日期 |
2012.04.27 |
| 申请人 |
MOLECULAR PARTNERS AG;JANSSEN BIOTECH, INC. |
发明人 |
JACOBS, STEVEN A.;O'NEIL, KARYN T.;BAUMANN, MICHAEL;SENNHAUSER, GABY |
| 分类号 |
C07K14/00;A61K38/16;A61P9/00;A61P11/00;A61P11/06;A61P17/00;A61P35/00;C12N1/19;C12N1/21;C12N5/10;C12N7/01;C12N15/11;C12N15/63;C12P21/02 |
主分类号 |
C07K14/00 |
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