发明名称 |
COATED MEDICAL DEVICES COMPRISING A WATER - INSOLUBLE THERAPEUTIC AGENT AND AN ADDITIVE |
摘要 |
A medical device includes an implantable structure and a coating layer including a water-insoluble therapeutic agent and one or more additives selected from heparin, heparan sulfate, dextran and dextran sulfate, and physiologically- acceptable salts thereof. The one or more additives can be present in an amount effective to increase the rate of release of the water-insoluble therapeutic agent from the coating layer. The implantable medical device structure can be an expandable structure such as a balloon or stent. Also described are methods of making and using such implantable medical devices and coating layers. |
申请公布号 |
CA2872464(A1) |
申请公布日期 |
2013.11.14 |
申请号 |
CA20132872464 |
申请日期 |
2013.05.08 |
申请人 |
COOK MEDICAL TECHNOLOGIES LLC |
发明人 |
BARBICK, JULIA E.;SHIRLEY, GARY B.;SARASAM, APARNA R.;GRABLE, CHARITY;BARNETT, ANGELA R. |
分类号 |
A61K9/00;A61F2/915;A61F2/958;A61K31/337;A61K31/715;A61K31/727;A61M25/10 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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