发明名称 |
Compositions for the treatment of CNS-related conditions |
摘要 |
The invention provides compositions comprising extended release memantine in combination with immediate release donepezil to a subject. Memantine in an extended release form containing 22.5 to 30 mg memantine or a pharmaceutically acceptable salt thereof in combination with donepezil achieves particular pharmacokinetic criteria such as change in plasma concentration of memantine over time and ratio of maximum memantine plasma concentration to mean memantine plasma concentration.
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申请公布号 |
US8580858(B2) |
申请公布日期 |
2013.11.12 |
申请号 |
US201213725246 |
申请日期 |
2012.12.21 |
申请人 |
ADAMAS PHARMACEUTICALS, INC. |
发明人 |
WENT GREGORY T.;FULTZ TIMOTHY J.;MEYERSON LAURENCE R. |
分类号 |
A01N47/28;A01N27/00;A61K9/00;A61K31/015;A61K31/17 |
主分类号 |
A01N47/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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