| 摘要 |
PROBLEM TO BE SOLVED: To provide new isomers of a metabolite of Iloperidone, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.SOLUTION: The invention provides an optical isomer of an Iloperidone metabolite P-88-8991, (R)-1-(4-{3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanol and (S)-1-(4-{3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanol, their preparation, their use as pharmaceuticals. |
