| 摘要 |
This disclosure describes, in one aspect, a composition that includes a beta-glucan component and an antibody component that specifically binds to the beta-glucan. In another aspect, this disclosure describes a method of increasing a subject's response to beta-glucan immunotherapy. Generally, the method includes identifying the subject as a low binder of beta-glucan and administering to the subject a composition that comprises a beta-glucan moiety conjugated to the therapeutic antibody. In some cases, the therapeutic antibody can be an anti-tumor antibody. |
| 申请人 |
BIOTHERA, INC.;GROSSMAN, WILLIAM J.;ANTONYSAMY, MARY A.;WALSH, RICHARD M.;NELSON, MARIANA I.;BOSE, NANDITA;DANIELSON, MICHAEL E.;MICHEL, KYLE S. |
发明人 |
GROSSMAN, WILLIAM J.;ANTONYSAMY, MARY A.;WALSH, RICHARD M.;NELSON, MARIANA I.;BOSE, NANDITA;DANIELSON, MICHAEL E.;MICHEL, KYLE S. |
