发明名称 DNA OLIGOMER THAT BINDS AS AN ANTISENSE TO THE HOMO SAPIENS INTERLEUKIN 24 MRNA
摘要 <p>The present invention relates to a method for suppress the expression of inflammation-related Homo sapiens interleukin 24 proteins by preparing a DNA fragment which complementarily binds to mRNA generated when Homo sapiens interleukin 24 gene is expressed. Su et al. elucidated the mechanism by which MDA7 selectively suppresses the growth of human breast cancer cells and the consequence of ectopic expression of MDA7 on human breast tumor formation in vivo in nude mice. They identified that interleukin 24 (IL-24) selectively induces apoptosis of human breast cancer cells and tumor growth in nude mice. In the present invention, 18 DNA nucleotides with respect to the upstream, midstream, and downstream of mRNA are synthesized and are injected to cells or tissues after dilution.</p>
申请公布号 KR20130121252(A) 申请公布日期 2013.11.06
申请号 KR20120044279 申请日期 2012.04.27
申请人 KIM, SEUNG CHAN 发明人 KIM, SEUNG CHAN
分类号 C12N15/63;C12N15/113;C12Q1/68 主分类号 C12N15/63
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