发明名称 |
SOLID DISPERSION FORMULATIONS AND METHODS OF USE THEREOF |
摘要 |
The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion. |
申请公布号 |
EP2654726(A4) |
申请公布日期 |
2013.10.30 |
申请号 |
EP20120754568 |
申请日期 |
2012.03.07 |
申请人 |
ZALICUS PHARMACEUTICALS LTD. |
发明人 |
PADVAL, MAHESH, V.;GAUTSCHI, JEFF, T.;SMITHEY, DANIEL, T.;CREW, MARSHALL, D.;HARIANAWALA, ABIZER |
分类号 |
A61K9/16;A61K9/48;A61K31/495 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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