发明名称 |
Compositions and coatings for delivery of therapeutic agents |
摘要 |
Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.
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申请公布号 |
US8568763(B2) |
申请公布日期 |
2013.10.29 |
申请号 |
US201213484086 |
申请日期 |
2012.05.30 |
申请人 |
ABUL-KHOUDOUD OMRAN R.;CAGIANNOS CATHERINE;DERIJK WALDEMAR G.;FABIAN TIMOTHY C.;JENNINGS LISA KYLE;THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION |
发明人 |
ABUL-KHOUDOUD OMRAN R.;CAGIANNOS CATHERINE;DERIJK WALDEMAR G.;FABIAN TIMOTHY C.;JENNINGS LISA KYLE |
分类号 |
A61F13/00;A61F2/00;A61F2/06;A61K9/14;A61L33/00 |
主分类号 |
A61F13/00 |
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