STRAIN OF BACTERIOPHAGE Escherichia coli ECD4, HAVING LYTIC ACTIVITY IN RESPECT TO BACTERIA Escherichia coli OF SEROTYPE O104:H4

摘要

FIELD: biotechnologies.SUBSTANCE: invention relates to a strain of the bacteriophage Escherichia coli ECD4. The strain of the bacteriophage Escherichia coli ECD4 is isolated from faeces of broiler chickens on the culture of the bacteria of the strain Escherichia coli O104.H4 RK1No.112027 and is deposited in the State Collection of Pathogenic Microorganisms and Cell Cultures "GKPM-Obolensk" under the number Ph63. The proposed strain of the bacteriophage has lytic activity in respect to the bacteria of the strain Escherichia coli O104:H4 RKINo.112027, lyses Escherichia of the serotype 0157:H7, does not suppress growth of cells Escherichia coli M-17, has lytic activity in respect to several other clinically significant serotypes of Escherichia, and also to several types of Shigella. The strain of the bacteriophage Escherichia coli ECD4 propagates on the laboratory non-pathogenic strain Escherichia coli K-12 C600F.EFFECT: invention may be used in creation of new preparations for treatment of a disease caused by bacteria Escherichia coli and for elimination of this pathogen from food products.4 ex