发明名称 |
PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES |
摘要 |
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification. |
申请公布号 |
WO2013158279(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
WO2013US31681 |
申请日期 |
2013.03.14 |
申请人 |
ABBVIE INC. |
发明人 |
RAMASUBRAMANYAN, NATARAJAN;YANG, LIHUA;HERIGSTAD, MATTHEW OMON;YANG, HONG |
分类号 |
C07K1/16;C07K1/18;C07K16/24 |
主分类号 |
C07K1/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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