发明名称 Excipient system for topical delivery of pharmaceutical agents
摘要 A pharmaceutical serum comprises (1) an alkyl lactate, wherein the alkyl group in the alkyl lactate contains from 2 to about 12 carbon atoms, (2) Simmondsia chinesis seed oil, and (3) a pharmaceutical agent. Preferably, the lactate is isoamyl lactate. The pharmaceutical agent may be selected from antifungal agents, hormones, growth factors (cytokines), antimicrobials, antibacterials, antibiotics, non-steroidal anti-inflammatory agents, immunodilators, anesthetics, plant extracts, vitamins, corticosteroids, and hair growth stimulants. A hair growth stimulant may be minoxidil, retinol or retinoic acid. An anti-fungal agent may be selected from tolnaftate or undecylenic acid. The pharmaceutical agent may also be carnosic acid, such as that found in rosemary extract. Peppermint oil and tea tree oil may also be present in the serum, which may be used in the treatment of onychomycosis, or for treating hair loss. The combination of an alkyl lactate and Simmondsia chinesis seed oil may allow penetration of the pharmaceutical agent through skin, fingernails and toenails.
申请公布号 GB201316049(D0) 申请公布日期 2013.10.23
申请号 GB20130016049 申请日期 2013.09.10
申请人 AD LUNAM LABS., INC. 发明人
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