CANCER THERAPY USING WHOLE GLUCAN PARTICLES AND ANTIBODIES
摘要
The present invention relates to methods of using whole glucan particles and complement activating antibodies for antitumor therapy. Whole glucan particles enhance the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. This binding enhances innate immune system cytotoxicity, as well as stimulating the release of activating cytokines.
申请公布号
EP1536820(B2)
申请公布日期
2013.10.23
申请号
EP20030749452
申请日期
2003.09.04
申请人
BIOPOLYMER ENGINEERING, INC.;UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.