| 发明名称 |
6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS |
| 摘要 |
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2C receptor agonists for the treatment of 5-HT2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where R6 is -C.ident.C-R10, -CH=CR11R11' , or -(C0-C8)alkyl-Ar2 optionally substituted on the alkyl moiety with 1 to 6 fluoro substituents and other substituents are as defined in the specification.
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| 申请公布号 |
CA2619287(C) |
申请公布日期 |
2013.10.22 |
| 申请号 |
CA20062619287 |
申请日期 |
2006.09.01 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
ALLEN, JOHN GORDON;BRINER, KARIN;CAMP, ANNE MARIE;CASES-THOMAS, MANUEL JAVIER;HOYING, RICHARD CHARLES;MARTINEZ-GRAU, MARIA ANGELES;MAZANETZ, MICHAEL PHILIP;POKROVSKAIA, NATALIA;RATHMELL, RICHARD EDMUND;ROTHHAAR, ROGER RYAN;SAPMAZ, SELMA;WILLIAMS, ANDREW CAERWYN |
| 分类号 |
C07D223/16;A61K31/55;A61P3/04;A61P25/00;A61P25/22;A61P25/24;C07D401/06;C07D403/04;C07D409/04;C07D417/06 |
主分类号 |
C07D223/16 |
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