发明名称 |
Enantiomerically pure compounds for the treatment of proliferative disorders |
摘要 |
The present invention relates to an enantiomerically pure (+)-trans enantiomer of a compound represented by the following formula (I): wherein R1, R2, R3, R4 and R9 are as defined in the specification; enantiomerically pure intermediates thereof, to processes for the preparation of the enantiomerically pure compound and its intermediates, and to a pharmaceutical composition comprising the enantiomerically pure compound. The compound of formula (I) is useful for the treatment of diseases or disorders mediated by the inhibition of cyclin dependant kinase, such as cancer.
|
申请公布号 |
US8563596(B2) |
申请公布日期 |
2013.10.22 |
申请号 |
US20060305815 |
申请日期 |
2006.06.21 |
申请人 |
SIVAKUMAR MEENAKSHI;MASCARENHAS MALCOLM;SARDE ANKUSH;JADHAV PRAMOD KUMAR;SHUKLA MANOJ;JOSHI KALPANA;RATHOS MAGGIE;PIRAMAL ENTERPRISES LIMITED |
发明人 |
SIVAKUMAR MEENAKSHI;MASCARENHAS MALCOLM;SARDE ANKUSH;JADHAV PRAMOD KUMAR;SHUKLA MANOJ;JOSHI KALPANA;RATHOS MAGGIE |
分类号 |
A01N43/36;A61K31/40;C07D207/00;C07D405/00;C07D409/00;C07D411/00 |
主分类号 |
A01N43/36 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|