摘要 |
<p>Methods are provided for determining the probability of lung cancer in patients with indeterminate pulmonary nodules. Also provided are methods for managing treatment of subjects with potential lung cancer. The methods can include determining an amount of each member of a panel of biomarkers in a sample from the subject, wherein, for example, the panel of biomarkers comprises at least two of the proteins alpha-1-antitrypsin, carcinoembryonic antigen, squamous cell carcinoma antigen, retinol binding protein, transferrin, and haptoglobin; and assigning the subject to a group having a higher or lower probability of lung cancer based on the determined amount of each biomarker the panel and based on the size of indeterminate pulmonary nodule.</p> |