PROCESS FOR PREPARING MEDIUM CHAIN DICARBOXYLIC ACIDS, CARBOXYLIC ACIDS AND ALCOHOLS FROM LONG CHAIN FATTY ACIDS

摘要

PURPOSE: A method for producing heavy chain dicarboxylic acids, carboxylic acids, and alcohols from long chain fatty acids is provided to produce a large amount of heavy chain dicarboxylic acids, carboxylic acids, and alcohols by enzyme reaction of a transformant which expresses Baeyer-Villiger monooxygenase (BVMO) and to safely and cheaply produce heavy chain dicarboxylic acids, carboxylic acids, and alcohols. CONSTITUTION: A transformant contains a gene encoding BVMO. BVMO is derived from Pseudomonas fluorescens, Pseudomonas putida, Pseudomonas veronii, Rhodococcus jostii, or Pseudomonas sp. strain HI-70. A method for producing heavy chain dicarboxylic acids, carboxylic acids, and alcohols from long chain fatty acids comprises the steps of: culturing the transformant in a medium containing the long chain fatty acids and obtaining a culture; and collecting heavy chain dicarboxylic acids and carboxylic acids or alcohols from the culture.