发明名称 |
Substituted pyrrolo-pyrazole derivatives as kinase inhibitors |
摘要 |
Compounds represented by formula (Ia) or (Ib) and wherein R and R1 are as defined in the description, and pharmaceutically acceptable salts thereof, are disclosed; the said compounds are useful in the treatment of cell cycle proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.
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申请公布号 |
US8557845(B2) |
申请公布日期 |
2013.10.15 |
申请号 |
US201213614545 |
申请日期 |
2012.09.13 |
申请人 |
BRASCA MARIA GABRIELLA;AMICI RAFFAELLA;FANCELLI DANIELE;NESI MARCELLA;ORSINI PAOLO;ORZI FABRIZIO;ROUSSEL PATRICK;VULPETTI ANNA;PEVARELLO PAOLO;NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
BRASCA MARIA GABRIELLA;AMICI RAFFAELLA;FANCELLI DANIELE;NESI MARCELLA;ORSINI PAOLO;ORZI FABRIZIO;ROUSSEL PATRICK;VULPETTI ANNA;PEVARELLO PAOLO |
分类号 |
A61K31/454;A61P17/00;A61P25/28;A61P35/00;C07D401/14;C07D487/00;C07D487/04 |
主分类号 |
A61K31/454 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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