发明名称 |
Method and apparatus for disrupting cells and amplifying nucleic acids using gold nanorods |
摘要 |
Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber. The apparatus comprises a cell disruption chamber comprising a sample inlet, and gold nanorods introduced therein; a laser attached to the cell disruption chamber, wherein the laser is for generating light at a wavelength absorbed by the gold nanorods; and a heater and a cooler for heating and cooling the cell disruption chamber. Also disclosed is a lab-on-a chip comprising the apparatus.
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申请公布号 |
US8557568(B2) |
申请公布日期 |
2013.10.15 |
申请号 |
US201113107677 |
申请日期 |
2011.05.13 |
申请人 |
CHEONG KWANG HO;YI DONG-KEE;LEE JEONG-GUN;PARK JONG-MYEON;SAMSUNG ELECTRONICS CO., LTD. |
发明人 |
CHEONG KWANG HO;YI DONG-KEE;LEE JEONG-GUN;PARK JONG-MYEON |
分类号 |
C12M1/34;C12M1/00;C12M3/00 |
主分类号 |
C12M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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