发明名称 |
METHODS FOR PREDICTING THE PROGNOSIS OF A SUBJECT WITH A MYELOID MALIGNANCY |
摘要 |
<p>One aspect of the present disclosure includes a method for predicting the prognosis of a subject with a myeloid malignancy. One step of the method includes obtaining a biological sample from the subject. Next, at least one mutation in a spliceosome-associated protein, or a polynucleotide encoding the spliceosome-associated protein that results in defective splicing can be detected in the biological sample. The presence of at least one mutation in the spliceosome-associated protein, or a polynucleotide encoding the spliceosome-associated protein, is indicative of the subject's prognosis.</p> |
申请公布号 |
WO2013151983(A1) |
申请公布日期 |
2013.10.10 |
申请号 |
WO2013US34926 |
申请日期 |
2013.04.02 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
MACIEJEWSKI, JAROSLAW;MAKISHIMA, HIDEKI;TIU, RAMON;VISCONTE, VALERIA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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