| 摘要 |
PROBLEM TO BE SOLVED: To provide cyclopenta [D] pyrimidines as AKT protein kinase inhibitors.SOLUTION: The present invention provides compounds of formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. In the formula I, A, R, R, R, Rand Rare each a substituent. The compounds are used for the treatment of hyperproliferative diseases such as cancer as AKT protein kinase inhibitors. |
