发明名称 |
Solid dispersion formulations and methods of use thereof |
摘要 |
The present invention relates to formulations and methods for increasing the bioavailability of 1- (4-benzhydrylpiperazin-l-yl)-3,3-diphenylpropan-l-one, l-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion. |
申请公布号 |
AU2012225459(A1) |
申请公布日期 |
2013.10.10 |
申请号 |
AU20120225459 |
申请日期 |
2012.03.07 |
申请人 |
ZALICUS PHARMACEUTICALS LTD. |
发明人 |
PADVAL, MAHESH V.;GAUTSCHI, JEFF T.;SMITHEY, DANIEL T.;CREW, MARSHALL D.;HARIANAWALA, ABIZER |
分类号 |
A61K31/54;A01N43/58;A61K31/4965;A61K31/50 |
主分类号 |
A61K31/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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