GENERATION OF MULTIFUNCTIONAL AND MULTIVALENT POLYPEPTIDE COMPLEXES WITH COLLAGEN XVIII TRIMERIZATION DOMAIN

摘要

The invention relates to the design of trimeric polypeptide complexes using polypeptide structural elements derived from the collagen XVIII protein, and their use in diagnostic and therapeutic systems in vivo and in vitro. The invention also relates to nucleic acids and vectors useful for producing said trimeric complexes.