发明名称 |
Crystalline ethyl 4-[4-[(2R)-3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-1-oxo-2-[[[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl]carbonyl]oxy]propyl]-1-piperazinyl]-piperidine-1-acetate difumarate |
摘要 |
The invention relates to the novel salts AB of the base A with a physiologically acceptable acid B which is selected from the group consisting of hydrochloric acid, hydrobromic acid, sulfuric acid, fumaric acid and salicylic acid and the polymorphic compounds, the corresponding solvates and hydrates thereof.
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申请公布号 |
US8551987(B2) |
申请公布日期 |
2013.10.08 |
申请号 |
US20080680060 |
申请日期 |
2008.09.25 |
申请人 |
PACHUR KATHRIN;RIES UWE JOERG;WERTHMANN ULRIKE;SPROLL SONJA;BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
PACHUR KATHRIN;RIES UWE JOERG;WERTHMANN ULRIKE;SPROLL SONJA |
分类号 |
C07D401/14;A61K31/551 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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