Composición farmaceutica compactada gastro-resistente que comprende 1 o mas enzimas autoesambladas, donde las enzimas retienen al menos 30% de su actividad después de la exposicion a fluido gastrico por 1 hora a 37°c; proceso de preparacion; y su uso en insuficiencia pancreatica exocrina parcial o completa, fibrosis quistica, entre otras

摘要

The present invention generally relates to compacted pharmaceutical compositions (such as tablets) comprising one or more enzymes, where the composition is monolithic or multiparticulates (such as mini-tablets, micro-tablets, or prills), or where the composition has multiple layers with the outermost layer containing one or more enzymes.