CURAXINS FOR USE IN TREATING BREAST CANCER AND METHOD FOR IDENTIFYING PATIENTS LIKELY TO RESPOND

摘要

The present invention relates to the treatment of breast cancer which is estrogen receptor positive (ER+) and/or human epidermal growth factor receptor 2 positive (HER2) and/or progesterone receptor positive (PR) and/or facilitates chromatin transcription positive (FACT +) with a curaxin, including curaxin 137. The presen invention also pertains to a method of identifying a subject who has a breast cancer tumor and is likely to respond to treatment with a curaxin.