发明名称 QUINOLINE DERIVATIVES AS RENIN INHIBITORS
摘要 A compound of formula (I), formula (I) or pharmaceutically acceptable salt thereof, as renin inhibitor, process of preparation thereof, and to the use of the compounds in the preparation of pharmaceutical compositions for the therapeutic treatment of cardiovascular disorders related to hypertension, in warm-blooded animals. Further the present invention also provides a method for treatment of disorders like congestive heart failure, cardiac hypertrophy, cardiac fibrosis, coronary artery disease, vasculopathy, neuropathy, intraocular hypertension, glaucoma, diabetic nephropathy, abnormal vascular growth, hyperaldosteronism etc.
申请公布号 WO2013088452(A3) 申请公布日期 2013.10.03
申请号 WO2012IN00726 申请日期 2012.11.06
申请人 SUN PHARMA ADVANCED RESEARCH COMPANY LTD. 发明人 THENNATI, RAJAMANNAR;SAMANTA, BISWAJIT;PAL, RANJAN KUMAR;KUMBHANI, ANIL SAVAJIBHAI;ADHYAPAK, JAY PRAKASHCHANDRA;AKOLKAR, NAKUL P;PARMAR, PRAVIN;DUBEY, MEGHA
分类号 C07D401/12;A61K31/4709;A61P9/12;C07D405/12;C07D491/04 主分类号 C07D401/12
代理机构 代理人
主权项
地址