发明名称 ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO[1,2-A][1,4]- BENZODIAZEPINES AND 6H-PYRROLO[1,2-A][1,4]BENZODIAZEPINES SUBSTITUTED WITH PHENYL DERIVATIVES
摘要 <p>The present invention is concerned with novel antifungal 5,6-dihydro-4H-pyrrolo-[1,2-a][1,4]benzodiazepines and 6H-pyrrolo[1,2-a][1,4]benzodiazepines of Formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</p>
申请公布号 EP2643324(A1) 申请公布日期 2013.10.02
申请号 EP20110784506 申请日期 2011.11.18
申请人 JANSSEN PHARMACEUTICA, N.V. 发明人 MEERPOEL, LIEVEN;MAES, LOUIS, JULES, ROGER, MARIE;DE WIT, KELLY
分类号 C07D487/04;A61K31/5517;A61P31/10 主分类号 C07D487/04
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