发明名称 |
DRUG DELIVERY SYSTEM FOR ADMINISTRATION OF A WATER SOLUBLE, CATIONIC AND AMPHIPHILIC PHARMACEUTICALLY ACTIVE SUBSTANCE |
摘要 |
A drug delivery system (DDS) for administration of a water soluble, cationic, and amphiphilic pharmaceutically active substance (API) which DDS comprises poorly water soluble nanoparticles formed by the API together with a Na-salt of N-all-trans-retinoyl cysteic acid methyl ester and/or a Na-salt of N-13-cis-retinoylcysteic acid methyl ester. A pharmaceutical composition comprising such a DDS. Methods for preparation of such a DDS and such a pharmaceutical composition. Use of such a DDS and pharmaceutical composition for treatment of cancer. |
申请公布号 |
EA018636(B1) |
申请公布日期 |
2013.09.30 |
申请号 |
EA20100070625 |
申请日期 |
2008.12.18 |
申请人 |
ARDENIA INVESTMENTS, LTD. |
发明人 |
ALEKSOV JULIAN;LOKOT IGOR |
分类号 |
A61K47/48;A61K9/14;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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