BROAD-SPECTRUM ANTIMICROBIAL COMPOSITIONS BASED ON COMBINATIONS OF TAUROLIDINE AND PROTAMINE AND MEDICAL DEVICES CONTAINING SUCH COMPOSITIONS

摘要

Novel antimicrobial compositions and coatings are disclosed. The antimicrobial compositions consist of mixtures of taurolidine and protamine, including protamine salts. The antimicrobial compositions are particularly useful in coatings for implantable medical devices. The antimicrobial compositions are effective against a broad spectrum of microbes.