| 发明名称 |
TREATMENT OF ALPHA-L-IDURONIDASE (IDUA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IDUA |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Alpha-L-Iduronidase (IDUA), in particular, by targeting natural antisense polynucleotides of Alpha-L-Iduronidase (IDUA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of IDUA.
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| 申请公布号 |
US2013253036(A1) |
申请公布日期 |
2013.09.26 |
| 申请号 |
US201113880409 |
申请日期 |
2011.10.20 |
| 申请人 |
COLLARD JOSEPH;KHORKOVA SHERMANN OLGA;COITO CARLOS;GANG SHEN;CURNA, INC. |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMANN OLGA;COITO CARLOS;GANG SHEN |
| 分类号 |
C12N15/113;C12N15/10;G01N33/53 |
主分类号 |
C12N15/113 |
| 代理机构 |
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